The free radical theory of aging (frta) states that organisms age because cells accumulate free radical damage over time a free radical is any atom or molecule that has a single unpaired electron in an outer shell. Free radicals will take (or leave) an electron, whether it’s available or not, including those in fragile dna molecules, proteins, and fats antioxidants stop free radical damage to molecules [ 6 ] by accepting or donating an electron to make it stable. Antioxidants and free radicals antioxidants are intimately involved in the prevention of cellular damage -- the common pathway for cancer, aging, and a variety of diseases.
Free radicals a free radical can be defined as any molecular species capable of independent existence that contains an unpaired electron in an atomic orbital the presence of an unpaired electron results in certain common properties that are shared by most radicals many radicals are unstable and highly reactive. The classic free-radical syndrome, the iron-storage disease hemochromatosis, is typically associated with a constellation of free-radical-related symptoms including movement disorder, psychosis, skin pigmentary melanin abnormalities, deafness, arthritis, and diabetes mellitus.
What causes free radicals to proliferate environmental pollutants, alcohol, smoking, unhealthy fats and even exercise generates added free radicals. Free radical definition is - an especially reactive atom or group of atoms that has one or more unpaired electrons especially : one that is produced in the body by natural biological processes or introduced from an outside source (such as tobacco smoke, toxins, or pollutants) and that can damage cells, proteins, and dna by altering their.
Major sources of free radicals so what causes free radicals to proliferate basically, the typical “western lifestyle” — with its processed foods, absence of healthy whole foods, reliance on medications and antibiotics, common use of alcohol or drugs, environmental pollutants, and high stress levelsfree radicals are generated due to oxidation and when toxins are broken down in the body. Normally, the body can handle free radicals, but if antioxidants are unavailable, or if the free-radical production becomes excessive, damage can occur of particular importance is that free radical damage accumulates with age.
Understanding free radicals and antioxidants describes what free radicals are and how a diet rich in antioxidants can combat them and prevent disease. Free radicals are molecules responsible for aging and tissue damage though some free radical damage is inevitable, some can be.
Free radicals are molecules with unpaired electrons they rob other cells of electrons, causing damage and contributing to many diseases. Free radicals, also known simply as radicals, are organic molecules responsible for aging, tissue damage, and possibly some diseases these molecules are very unstable, therefore they look to bond with other molecules, destroying their health and further continuing the damaging process. Free radicals a free radical can be defined as any molecular species capable of independent existence that contains an unpaired electron in an atomic orbital.
The result is what we call a free radical cascade, an enormous chain reaction of free radicals that quickly wreaks havoc on living tissue it is estimated that the chain reaction can trigger 6023 x 10 21 billion molecules to react per second. Once a free radical forms and it succeeds in gaining another electron from a nearby molecule, it leaves its victim short an electron and has now made this new molecule a free radical, which will in turn, try and steal an electron as well.
The free-radical theory of aging proposes that radicals underlie the aging process itself similarly, the process of mito hormesis suggests that repeated exposure to radicals may extend life span.